Amsterdam 2015
Menu
AIDSImpact.com
Conference Details
Authors
International Committee
Plenary Speakers
Presenting Speakers
Programme
Sessions
Scientific Committee
Acknowledgements
| Abstract #2339 - Mad about the boy - MSM II | ||||
|
Session: 41.3: Mad about the boy - MSM II (Parallel) on Thursday @ 16.30-18.00 in C104 Chaired by Hycienth Ahaneku, Jeffrey Kelly Authors: Presenting Author: Mr Dr Ulrich Marcus - Robert Koch-Institute, Germany |
||||
| Additional Authors: | ||||
| Aim: In countries with unrestricted access to antiretroviral treatment undiagnosed HIV infections are thought to be the main sources of new HIV infections. However, little is known about characteristics and sexual behaviours of people with undiagnosed infections. Some information can be collected and analysed in HIV testing sites from people newly diagnosed with HIV, but people presenting for testing self- and therefore such samples may be biased. We analysed data from a large multicity European bio-behavioural survey among men having sex with men (MSM). | ||||
| Method / Issue: In 2013/2014 MSM were recruited for a bio-behavioural survey (SIALON II) using time-location-sampling (TLS) in nine and respondent-driven-sampling (RDS) in four major European cities. Participants filled in a short questionnaire and provided an oral fluid (TLS) or blood (RDS) specimen for HIV antibody testing. Participants were defined as HIV-negative, known HIV-positive, and as yet undiagnosed HIV-positive (1) based on self-reported and laboratory-determined HIV antibody status. The latter were further divided into incident cases (1a - negative test result within the previous 12 months) and cases with unknown duration of infection (1b). We analysed demographics, sexual behaviours in the previous six months and during last anal intercourse (AI), and sex-related drug use comparing men with undiagnosed HIV and the two subgroups with HIV-negative men using bivariate and multivariate logistic regression analysis. | ||||
| Results / Comments: A valid HIV test results was available for 4,716 participants. As yet unknown HIV infection was diagnosed in 163 cases (3.5%), among them 112 were incident, 51 were not. No significant associations were detected between undiagnosed infection (1) and Global AIDS Response Progress (GARP)-indicators 1-11 (reached by prevention programmes), 1-12 (condom use last anal intercourse), 1-13 (HIV-testing in last 12 months), types of partners (steady, non-steady, both) in the last 12 months, reported HIV seroconcordance with last anal sex partner (concordant, discordant, non-concordant), and reporting of any unprotected AI(UAI) in the last 12 months. In multivariate analysis, having used party drugs (ghb, ecstasy, cocaine, amphetamine) or poppers in the context of last AI, being versatile during last AI, and having been recruited in Lisbon were positively, being younger than 25 years was negatively associated with undiagnosed incident HIV (1a). Only age 35-44 and reporting more than 4 UAI partners were positively associated with undiagnosed non-recent infection (1b). Partner numbers, having been recruited in a sex venue (TLS), and six more cities were significant in bivariate, but not in multivariate analysis. | ||||
| Discussion: Established indicators (GARP) and expected risk factors (UAI, relationship status) could not be confirmed as being associated with undiagnosed HIV infection (1) in European MSM. This may be due to preion of the sample or may be an indication of quite successful individual management of known HIV risk factors by a broad array of preventive tactics. The use of party and sex drugs may abrogate successful risk management, or versatility and party sex drug use may be surrogates for unmeasured other characteristics associated with infection risk. Men reporting >4 UAI partners in the last six months might benefit from new prevention tools such as pre-exposure prophylaxis. | ||||
| Go Back | ||||