Amsterdam 2015
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| Abstract #2258 - Biomedical prevention | ||||
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Session: 13.6: Biomedical prevention (Oral poster discussion) on Wednesday @ 13.30-14.30 in Poster room 2 Chaired by Catherine Hankins, Sara Paparini Authors: Presenting Author: Ms Marjory Corbinaud - SIS Réseau, France, Metropolitan |
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| Additional Authors: | ||||
| Aim: 150,000 people live with HIV in France (PLWHIV) and around 90,000 are on antiretroviral therapy treatment (ART). Pharmacological and dosage form evolutions in ART and their use as prevention have modified the everyday life of PLWHIV. Sida Info Service – the French HIV/AIDS helpline – conducted a national cross-sectional survey from July to October 2014 examining treatment adherence from the perspective of how therapy and its challenges are incorporated into everyday life. | ||||
| Method / Issue: Both quantitative and qualitative data were collected through an anonymous questionnaire. Analysis of the sample (n=367) was realized with Modalisa©. | ||||
| Results / Comments: 22% of participants had already voluntarily stopped their present treatment for several days, of whom 39.5% to reduce adverse side-effects, and 33.8% of them without telling their doctor. At the start of treatment fear of possible side-effects remains high: four PLWHIV treated for less than two years out of five. Two thirds of participants experience problematic side effects, of whom 27.8% on a regular basis. Regular side-effects concern more often PLWHIV treated for longer than 20 years (49.1%), women (40%), people not on single-tablet therapy (38.6% on multi-dose combination therapy, 30.7% on once-daily multi-tablet therapy), and those with insufficient financial resources (37.3%). 35.7% of PLWHIV who often experience problematic side-effects believe that treatment does not benefit their health and 23.8% feel discouraged about continuing. 26.5% of PLWHIV who experience side-effects all the time do not feel sufficiently informed by their doctor and 42.9% of them feel that their doctor does not listen to them. | ||||
| Discussion: Problematic side-effects alter perception of anti-HIV drugs and the doctor-patient relationship, with negative consequences on adherence. Some improvement approaches are emerging: wider range of single-tablet regimen treatments, information development and support targeting specific groups (women, people beginning treatment or aging with HIV, living on limited financial means), studies on alternating drug regimens, and addressing stigmatization issues. | ||||
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