Amsterdam 2015
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| Abstract #2236 - Comorbidity - double jeopardy | ||||
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Session: 23.4: Comorbidity - double jeopardy (Parallel) on Wednesday @ 16.30-18.00 in 202 Chaired by Margalit Lorber, Simon Rackstraw Authors: Presenting Author: Dr. Y. Alicia Hong - Texas A&M University, United States |
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| Additional Authors: | ||||
| Aim: More than 72% of cancer deaths and 70% of HIV infections are found in low and middle income countries (LMIC). Despite the fact that people living with HIV/AIDS (PLWHA) are at higher risk of developing cancer, cancer screening among PLWHA in LMIC is limited. This study systematically reviews existing studies on cancer screening among PLWHA in LMIC, identifies literature gaps and makes recommendations for future research. | ||||
| Method / Issue: Major databases including Medline, EBSCO, Web of Science, and Google Scholar were searched with key words of cancer screening and HIV. The following ion criteria were used: 1) studies conducted on PLWHA, 2) studies conducted in LMIC, 3) studies reporting effects or outcomes of screening. Additional articles were identified by hand searching the references of identified articles. All articles were critically appraised and key data were entered into matrices for analysis. | ||||
| Results / Comments: A total of 16 studies were included in the review, including 13 conducted in the sub-Saharan Africa, 2 in Asia, and 1 in South America. Fourteen studies were focused on cervical cancer screening among female PLWHA and the remaining two were about anal cancer screening among males. A majority of the studies were evaluating or comparing various screening methods, such as VIA, cervical cytology and HPV testing. The study sample size ranged from 303 to 15081, but half of the studies had a sample size of less than 500. The rates of cervical lesions varied across the studies and only 7 studies confirmed their results by colposcopy (gold standard) with rates varying from 4.4-27.4%. | ||||
| Discussion: Studies on cancer screening among PLWHA in LMIC are very scarce. Existing studies were limited by lack of rigorous design, insufficient sample size, and without confirmation of gold standard in screening results. With advancement of HIV testing and treatment, the number of PLWHA will continue to increase, it’s important to carry out routine cancer screening among PLWHA. We call for more culturally appropriate studies on cancer prevention and screening among PLHWA in LMIC. | ||||
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