Amsterdam 2015
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| Abstract #2160 - PrEP | ||||
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Session: 50.7: PrEP (Symposium) on Friday @ 11.00-12.30 in C103 Chaired by John de Wit, Veronica Noseda Authors: Presenting Author: Ms Rojas Castro Daniela - AIDES, France |
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| Additional Authors: | ||||
| Aim: In July 2012, the FDA approved the use of TDF/FTC as pre-exposure prophylaxis (PrEP) for individuals at high risk of HIV infection. In 2014, the USA Public Health Service published the first clinical practice guidelines for PrEP and, WHO consolidated guidelines on HIV prevention also recommended PrEP use. In France, the community-based organization AIDES is currently lobbying for access to PrEP and in this context decided to conduct a survey to know who would be interested in using it. | ||||
| Method / Issue: A nationwide survey was proposed to all AIDES users from 31st March to 13th April 2014. An on-line version of the questionnaire was available from April 28th to May 31st. The questionnaire started with a brief explanation of what PrEP is and of the protocol (follow-up, HIV and other STI screening, counseling sessions) that would be offered if PrEP was authorised by health authorities. Three main dimensions were evaluated: PrEP knowledge, willingness and intention. Analyses were carried out by correcting the sampling bias between paper and on-line versions of the survey. Statistical analysis was performed using SPSS® statistical software (version 17). | ||||
| Results / Comments: 3,024 HIV-negative people filled in the survey. Their main characteristics were: median age 32, 32.8% were French, 64.4% had a post graduate degree, 19.3 % were heterosexual men, 47.5% were men who have sex with men (MSM) and 28.9% were heterosexual women. Results showed that 33.4% of respondents were aware of PrEP, 49% were interested in using PrEP as part of a comprehensive prevention response, 11.1% declared intention to use PrEP « without any doubt » and 25.6% declared « they would need more information » before using it. Informal PrEP use was reported by 4.5% of respondents. Factors associated with intention to use PrEP without hesitation were: having a clear perception of one’s risk of being infected with HIV (OR(CI95%] 4,05[1,888,74]), being 25-29 years old (1,97[1,372,82]) or being over 50 (2,59[1,654,07]), declaring an adequate financial situation (2,36[1,683,3]), not having a university degree (2,35[1,324,17] ), having informally used PrEP at least once in their life time (2,28[1,513,45]), having had more than 2 HIV tests in the previous 12 months (2,16[1,463,2]), being born abroad (1,85[1,342,55]), having children (1,78[1,292,45]), having a HIV-positive main partner (1,59[1,002,53]). Intention to use PrEP was less likeky among MSM, compared to heterosexual men (0,64[0,440,92]), and among respondents thinking that PrEP is an inappropriate prevention tool (O0,39[0,250,61]). | ||||
| Discussion: These first results regarding knowledge, willingness and intention to use PrEP in France show that heterosexual people, migrants and most-at-risk people declare higher intention of using PrEP. The results obtained regarding willingness (42.7%) and intention (11.1%) are particularly interesting, since willingness compared to intention has been widely used in PrEP literature. These results should be used to design adequate PrEP delivery service and are in line with the first analysis of PrEP delivery in the USA. | ||||
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