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Abstract #2131 - Circumcision and TasP: Biomedical interventions
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Session: 27.1: Circumcision and TasP: Biomedical interventions (Parallel) on Thursday @ 11.30-13.00 in C001 Chaired by Catherine Adams, Fraukje Mevissen
Authors: Presenting Author: Dr. Daniel Montano - University of Washington, United States
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Additional Authors:
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Aim: Male circumcision (MC) is one of the most effective biomedical HIV-prevention strategies, requiring high uptake to maximize the impact on the epidemic. This impact may be offset by at least two factors: 1) MC participation bias skewed toward men at lowest risk, 2) risk compensation (RC) among men who get MC. The prevalence of these factors in a national MC program is unknown and is being assessed in a longitudinal study of men in Zimbabwe. The baseline survey results will assess whether there is lower risk among men getting MC. RC will be assessed in follow-up surveys.
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Method / Issue: We enrolled a cohort of 2391 HIV-negative men age 18-40 in two urban cities in Zimbabwe, 1200 recently circumcised and 1191 not circumcised. Participants were enrolled in a study comprised of interviews assessing psychosocial and behavioral variables at baseline, 6, 12, and 24 months, with HIV testing at 24 months. Baseline data collection is complete and allowed us to assess similarity between the two groups at recruitment. We compared the two cohorts on sexual behavior including age at sexual debut, number of partners in the last 6 months, past year and lifetime, sex with sex workers, same sex partners, condom use, concurrent partnerships, and alcohol and drug use.
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Results / Comments: The MC group reported more sexual partners in the last 6 months, 12 months, and lifetime, and was more likely to report concurrent partnerships, but the differences were not statistically significant. The MC group reported sexual debut significantly later than the non-MC group (19.5 year and 19.1 years respectively p<.004). The non-MC group reported more contact with sex workers but the difference was not significant. There was no difference in the probability of having ever used alcohol or marijuana, but the non-MC group drank alcohol and smoked marijuana on significantly more occasions in the prior 30 days.
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Discussion: There are no clear or consistent differences in risky behaviors between the MC and non-MC groups at baseline. These findings indicate that in Zimbabwe there appears to be no bias toward lower sexual risk among those electing MC, and confirms that our two cohorts are similar at baseline. Analysis of follow-up surveys will determine whether RC occurs after MC.
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