Barcelona 2013
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| Abstract #379 - E-Posters English | ||||
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Session: 50.86: E-Posters English (Poster) on Sunday in Chaired by Authors: Presenting Author: Dr Pep Coll - IrsiCaixa, Spain |
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| Additional Authors: Dr. Jordi Casabona, Sra Cristina Sanclemente, Dra. Anna Esteve, Dra. Victoria Gonzalez, Grupo HIVITS TS, | ||||
| Aim: A cohort of MSM at higher risk of infection was set up as a shared project of researchers and the community: the HIV vaccine research programme in Catalonia (HIVACAT) and a community centre for the detection of HIV in MSM (BCN Checkpoint), with the objective of early diagnosis of HIV and other sexually transmitted infections (STIs) | ||||
| Method / Issue: : Participation in this cohort was offered to MSM in Barcelona by specific advertising in a community HIV testing centre. Individuals at higher risk of infection were selected through an initial risk-assessment questionnaire. Participants were screened on a quarterly basis for HIV infection, and once a year for other STIs: serologies for syphilis, hepatitis A, B and C. PCR for C. trachomatis and N. gonorrhoeae in penis and anus. Also HPV in anus and mouth was screened by PCR, together with an anal cytology. A High Resolution Anuscopy was performed if a dysplasia was detected. To ensure the involvement of the community, the study protocol was reviewed by the local Community Advisory Board | ||||
| Results / Comments: Between December 2010 and August 2012, 268 individuals were recruited, 44 lost of follow up, and 10 acute HIV infections were detected (incidence: 2,3 per 100 persons/year). Prevalence of STI at baseline visit were: syphilis 8,2% (95% CI: 6,5-9,9), C. trachomatis in penis 3% (95% CI: 1-5), in rectum 6,1% (95% CI: 4,9-7,3) , N. gonorrhoeae in penis 1,9% (95% CI:-1,5-5,3) , in rectum 5% (95% CI: 2,4-7,6), HPV in anus 65,6% (95% CI: 62,8-68,4) , in mouth 3,7% (95% CI: 0,7-6,7). Cytological abnormalities were detected in 42% (95% CI: 36,1-47,9) of individuals. No acute hepatitis diagnosed. All cases detected were treated in situ or referred for assessment and treatment | ||||
| Discussion: The establishment of this kind of cohorts, with a close collaboration between community and researchers, allows identifying early HIV infections and asymptomatic STIs among individuals at high risk. An adequate linkage to health care ensures the continuity of care, helping to break the chain of infection | ||||
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