Barcelona 2013
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| Abstract #210 - E-Posters English | ||||
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Session: 50.37: E-Posters English (Poster) on Sunday in Chaired by Authors: Presenting Author: Dr. Kelly O'Brien - University of Toronto, Canada |
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| Additional Authors: Dr. Jordi Casabona, Sra Cristina Sanclemente, Dra. Anna Esteve, Dra. Victoria Gonzalez, Grupo HIVITS TS, | ||||
| Aim: The HIV Disability Questionnaire (HDQ) is a 69 item self-administered questionnaire, developed in Canada, that measures disability experienced by people living with HIV. The HDQ is comprised of six domains including physical symptoms and impairments (20 items); cognitive symptoms and impairments (3 items); emotional and mental health symptoms and impairments (11 items), uncertainty (14 items), difficulties with day-to-day activities (9 items) and challenges to social inclusion (12 items). Our purpose was to assess internal consistency reliability, and construct validity of the HDQ with adults living with HIV in Canada and Ireland. | ||||
| Method / Issue: We recruited adults 18 years of age or older living with HIV who self-identified as having experienced an episode of illness attributed to HIV from hospital clinics and AIDS service organizations in southern Ontario, Canada and Dublin, Ireland. We administered the HDQ paired with reference measures (World Health Organization Disability Assessment Schedule, SF-36 Questionnaire, Medical Outcomes Study Social Support Survey), and a demographic questionnaire. We calculated HDQ disability presence, severity and episodic scores (scored from 0-100). We calculated internal consistency coefficients (Cronbach?s alpha (á) and Kuder-Richardson-20), for the disability and episodic scores, respectively and considered coefficients >0.80 acceptable for a research instrument. To assess construct validity, we tested 40 a priori hypotheses of correlations between scores on the HDQ and reference measures and two known group hypotheses comparing HDQ presence and severity scores based on age and comorbidity. Irish and Canadian populations were analyzed separately. We considered acceptance of at least 75% of hypotheses as demonstrating support for construct validity. | ||||
| Results / Comments: Of the 235 participants (139 Canada; 96 Ireland), the majority were men (74% Ireland; 82% Canada) and were taking antiretroviral therapy (88% Ireland; 91% Canada). Compared with Irish participants, Canadian participants were older (median age: 48 versus 41 years) and reported living with a higher median number of comorbidities (4 versus 1, p=0.0001). Highest median disability presence scores were in the cognitive (Canada:100) and uncertainty domains (Ireland:71). Highest median disability severity scores were in the uncertainty domain (39 Canada; 30 Ireland). The median episodic score, representing the number of challenges that fluctuated in the past week, was highest in the physical symptoms and impairments domain (20 Ireland; 18 Canada). Median HDQ severity and presence scores were higher among Canadian participants across all domain and total scores (p=0.0001), except for uncertainty. The internal consistency coefficients for Irish and Canadian participants were 0.973 (95% confidence interval (CI): 0.967-0.980) and 0.965 (95%CI: 0.954-0.976), respectively, for the severity scale and 0.978 (95%CI: 0.971-0.984) and 0.963 (95% CI: 0.950-0.976), respectively, for the episodic scale. Of the 40 construct validity hypotheses, 32(80%) and 22(55%) were supported among the Canadian and Irish populations respectively; both (100%) known group hypotheses were also supported. | ||||
| Discussion: The HDQ demonstrates internal consistency reliability and construct validity when administered to adults living with HIV in southern Ontario and Ireland. Differences in construct validity between Ontario and Ireland may be due to lower HDQ scores among Irish participants who were younger and reported less comorbidity, cultural differences, and differences in HDQ interpretation. | ||||
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